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Lieu phap moi: Chong ung thu bang te bao bach cau

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Lieu phap moi: Chong ung thu bang te bao bach cau

Mot lieu phap chong ung thu co hieu qua 100% tren chuot dang duoc cac chuyen gia truong DH Wake Forest, Bac Carolina, Hoa Ky, chuan bi thu nghiem lam sang tren con nguoi.
Khoi ung thu thanh quan.

Lieu phap moi: Chong ung thu bang te bao bach cau

Sau nhung thu nghiem  thanh cong  tren chuot va tren te bao ung thu cua nguoi trong phong thi nghiem, “lieu phap truyen bach cau” (Leukocyte InFusion Therapy - LIFT) cua TS. Zheng Cui va cac cong su da duoc Co quan Quan ly  Thuc pham  va Duoc pham Hoa Ky  (FDA) cho phep thu nghiem  tren 22 benh nhan mac cac benh ung thu khac nhau.

Lieu phap nay su dung te bao bach cau de tan cong  vao khoi u va tieu diet te bao ung thu. Nhung te bao bach cau do se duoc cho boi nhung nguoi tinh nguyen co he mien dich san xuat duoc bach cau hat (granulocyte) co hoat tinh chong ung thu cao.

Theo cac chuyen gia, bach cau hat la loai te bao co the chiem den 60% trong tong so te bao bach cau o nguoi khoe manh. Bach cau hat se duoc lay rieng ra de su dung bang phuong phap tach cac thanh phan cua mau (apheresis), nen nguoi cho bach cau se khong bi mat nhung thanh phan khac cua mau.

Nhom nghien cuu  cho biet cac thu nghiem  vua qua tren chuot bi ung thu da dat ti le thanh cong  la 100%. TS. Zheng Cui noi: “O chuot, chung toi  da co the tieu diet duoc te bao ung thu, tham chi ca nhung khoi u ac tinh co kich thuoc  lon. Chung toi  hy vong ket qua tuong tu se xay ra khi thu nghiem  tren nguoi”.

Nhom nghien cuu  dang chuan bi tuyen chon 500 nguoi tinh nguyen tu 50 tuoi tro xuong co suc khoe  tot de xet nghiem mau. Trong so nay, se chon ra 100 nguoi co bach cau manh nhat de tham gia cuoc thu nghiem  sap toi.  

Yeu to then chot de lieu phap nay thanh cong  la truyen cho benh nhan du luong bach cau hat co kha nang giet chet te bao ung thu o muc cao nhat. Theo TS. Cui, “lieu phap nay khac voi cac lieu phap su dung bach cau thong thuong o cho nguoi cho bach cau duoc chon tren co so bach cau cua ho co hoat tinh manh doi voi ung thu”. 

Giao su benh ly hoc Mark  Willingham, thanh vien  nhom nghien cuu, phat bieu: "Day la ket qua cua gan 10 nam nghien cuu  ke tu khi chuot khang ung thu lan dau tien duoc kham pha vao nam 1999. Neu cuoc thu nghiem  sap toi thanh cong, LIFT se tro thanh mot loai vu khi  moi de chong ung thu”.

TS. Zheng Cui noi: “Du chua the doan truoc dieu gi se xay ra, nhung chung toi  hy vong lieu phap nay se chua duoc mot so benh ung thu va cuu duoc mot so nguoi trong vai thang toi”.

Tim bai viet khac
Theo VietNamNet
Updated: 03/07/2008 | Views: 111 | Comments: 0

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